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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP2K3
All Species:
13.94
Human Site:
Y214
Identified Species:
25.56
UniProt:
P46734
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46734
NP_002747.2
347
39318
Y214
C
D
F
G
I
S
G
Y
L
V
D
S
V
A
K
Chimpanzee
Pan troglodytes
Q9XT09
393
43428
G250
Q
S
D
I
W
S
M
G
L
S
P
V
E
M
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546666
347
39324
Y214
C
D
F
G
I
S
G
Y
L
V
D
S
V
A
K
Cat
Felis silvestris
Mouse
Mus musculus
O09110
347
39278
Y214
C
D
F
G
I
S
G
Y
L
V
D
S
V
A
K
Rat
Rattus norvegicus
Q4KSH7
419
47517
L268
D
F
G
I
S
G
R
L
V
D
S
K
A
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511595
352
40240
Y219
C
D
F
G
I
S
G
Y
L
V
D
S
V
A
K
Chicken
Gallus gallus
Q90891
398
44059
V256
W
S
M
G
L
S
L
V
E
L
S
I
G
R
Y
Frog
Xenopus laevis
Q07192
446
50082
Q300
C
D
F
G
I
S
G
Q
L
V
D
S
I
A
K
Zebra Danio
Brachydanio rerio
Q9DGE0
361
40575
I227
V
K
M
C
D
F
G
I
S
G
Y
L
V
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477162
334
38176
A202
G
Y
L
V
D
S
I
A
K
T
I
D
A
G
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20347
363
41178
Q218
C
D
F
G
I
C
G
Q
L
E
E
S
F
A
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJV0
356
39818
S220
G
V
S
A
S
L
A
S
S
M
G
Q
R
D
T
Baker's Yeast
Sacchar. cerevisiae
P08018
668
72701
V512
F
G
V
S
G
N
L
V
A
S
L
A
K
T
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.7
N.A.
99.1
N.A.
96.5
37.2
N.A.
89.7
30.3
42.1
75.3
N.A.
57
N.A.
37.7
N.A.
Protein Similarity:
100
47
N.A.
99.7
N.A.
98.8
56.7
N.A.
93.1
48.7
58
84.4
N.A.
72.9
N.A.
55.6
N.A.
P-Site Identity:
100
13.3
N.A.
100
N.A.
100
0
N.A.
100
13.3
86.6
13.3
N.A.
6.6
N.A.
66.6
N.A.
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
6.6
N.A.
100
26.6
93.3
13.3
N.A.
6.6
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
23.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.2
35.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
8
8
0
0
8
16
47
8
% A
% Cys:
47
0
0
8
0
8
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
47
8
0
16
0
0
0
0
8
39
8
0
16
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
8
8
0
8
0
0
% E
% Phe:
8
8
47
0
0
8
0
0
0
0
0
0
8
0
0
% F
% Gly:
16
8
8
54
8
8
54
8
0
8
8
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
16
47
0
8
8
0
0
8
8
8
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
8
0
0
8
8
8
47
% K
% Leu:
0
0
8
0
8
8
16
8
54
8
8
8
0
0
0
% L
% Met:
0
0
16
0
0
0
8
0
0
8
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
16
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
8
8
0
% R
% Ser:
0
16
8
8
16
62
0
8
16
16
16
47
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
16
% T
% Val:
8
8
8
8
0
0
0
16
8
39
0
8
39
0
0
% V
% Trp:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
31
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _